Chemical Name: 9-Fluoro-11β-hydroxy-16β-methyl-3,20-dioxopregn-4-ene-17,21-diyl dipropanoate (as per EP)
Synonym: 1,2-Dihydrobetamethasone dipropionate (EP)
Smiles: O=C([C@]([C@]([C@@]1([H])C2)(C[C@H](O)[C@](F)([C@]3(CC4)C)[C@@]1([H])CCC3=CC4=O)C)([C@H]2C)OC(CC)=O)COC(CC)=O
Inchi: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1/i3D,7D2,10D,17D,20D
Application of LC–MSn in conjunction with mechanism-based stress studies in the elucidation of drug impurity structure: Rapid identification of a process impurity in betamethasone 17-valerate drug substance
Min Li, Mingxiang Lin, Abu Rustum
Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 1451–1456
Development and Validation of Stability-indicating HPLC Method for Betamethoasone Dipropionate and Related Substances in Topical Formulation
A. s. vairale*, p. sivaswaroop1 and s. bandana
Indian Journal of Pharmaceutical Sciences 74(2):107-15