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Azithromycin Dihydrate

N° de SZ CAT SZ-A040000
Número CAS 117772-70-0
Mol.F. C38H72N2O12 : 2H2O
Peso Molecular 749.0 : (18.0)
Status de Fatura In Stock
Rel. CAS No 83905-01-5 (free base) ; 121470-24-4 (hydrate) ; 90581-30-9 (HCl salt)
Shipping Condition Ambient Temperature


Disclaimer

SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one dihydrate (as per EP) ; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-l-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-d-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one dihydrate (as per USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: C[C@@H]([C@@H]([C@H](C(O[C@@H]([C@@](C)(O)[C@@H]1O)CC)=O)C)O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@@]2(C)OC)[C@H]([C@](O)(C[C@H](CN([C@@H]1C)C)C)C)O[C@@](O[C@H](C)C[C@@H]3N(C)C)([H])[C@@H]3O.[2H2O]

Azithromycin Dihydrate is chemically (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one dihydrate (as per EP) ; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-l-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-d-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one dihydrate (as per USP). Azithromycin Dihydrate is supplied with detailed characterization data compliant with regulatory guideline. Azithromycin Dihydrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Azithromycin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Determination of azithromycin in raw materials and pharmaceutical formulations by HPLC coupled with an evaporative light scattering detector
Aiguo Zenga, Xia Liua, Siruo Zhangb, Yan Zhengc, Ping Huangc,Kangli Dua, Qiang Fu
Asian Journal of Pharmaceutical Sciences 9(2):107–116
 
LC determination of impurities in azithromycin tablets
L. Miguel, C. Barbas
Journal of Pharmaceutical and Biomedical Analysis 33 (2003) 211/217
 
Agglomeration Mechanism of Azithromycin Dihydrate in Acetone− Water Mixtures and Optimization of the Powder Properties
Songgu Wu,†,‡ Huan Shen,†,‡ Kangli Li,†,‡ Bo Yu,†,‡ Shijie Xu,†,‡ Mingyang Chen,†,‡ Junbo Gong,*,†,‡ and Bao hong Hou
Ind. Eng. Chem. Res. 2016, 55, 17, 4905–4910
 
Characterization of four unknown impurities in azithromycin and erythromycin iminoether by 2D LC/Q-TOF MS and NMR
Yong jina, , Xu Yub , Jinjin Zhoub , Zhikui Zhoua , Jian Wang
Rapid Commun Mass Spectrom. 2020 Jun 15;34(11):e8772.
 
Analysis of Azithromycin and Its Related Compounds by RP-HPLC with UV Detection
Fuad Al-Rimawi1 and Maher Kharoaf
Journal of Chromatographic Science, Vol. 48, February 2010
 
Development and Validation of RP- UHPLC Method for Azithromycin and Its Related Compounds in Tablet Dosage Form
Santosh Kumar Bhardwaj*1,2, Dau Dayal Agarwal1 , Vivek Sharma1 and Subodh Kumar Budakoti
Journal of Chemical and Pharmaceutical Research, 2016, 8(7):113-122

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Delivery time:
  • In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
  • The custom synthesis products would be dispatched as per quoted timeline.

Shipping:
  • There will be 100 USD towards logistic charges per shipment if we used our FedEx. There will not be any charge if we use your FedEx/DHL Account. Depending on part shipment logistic charges will be added.
  • For countries dispatch by courier is not allowed where product would be dispatched in cargo mode as per agreed Inco term.

Additional Charges:
  • Controlled substance charges need to follow as per quotation. The specific inputs are required for controlled substance because regulatory status will differ based on destination.
  • Cold Shipment Charges needs to be considered as per quotation.
  • For ice pack there are no additional charges.

Technical Queries:
  • All technical queries need to raise within 15 days of product receipt. Thereafter it will be our resolved at our discretion.

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